Trigonelline

Trigonelline promotes cellular NAD+ production differently than other precursors such as NMN or NR.

This methylated form of Niacin has advantages over other forms of this B vitamin:

• Exceptional stability in bloodstream
  
• Slow release into target tissues
  
• Non-flushing
  
• Protected against digestion in the stomach
  
• Increases NAD+ directly in muscle (unlike NMN or NR)

Trigonelline (methylated niacin) is an NAD+ precursor that promotes NAD+ production in muscle cells, a property not observed in other NAD+ boosters like NMN or NR. It accomplishes this through conversion in the Preiss-Handler pathway, unlike other NAD+ precursors which utilize the Salvage pathway. Its innate bioavailable structure allows it to survive digestion, cross the blood-brain barrier, and directly stimulate NAD+ production in muscle, brain, and other tissues.

Trigonelline, as a methylated form of Niacin, actively promotes NAD+ restoration in muscle cells. While NMN and NR can increase NAD+ metabolites in muscle, there has been no evidence to indicate that either of these precursors actively increase NAD+ concentration in muscle, making Trigonelline the only precursor known to have this benefit.

Take one (1) capsule daily with or without food.

• If you are pregnant, nursing, or trying to conceive, taking any medications, or have a medical condition, please consult your healthcare provider before taking any supplements.
• This product is contraindicated in an individual with a history of hypersensitivity to any of its ingredients.
• Keep out of the reach of children.
• Do not use if tamper evident or if safety seal is broken or missing.
• This product is not intended to diagnose, treat, cure, or prevent any disease. For nutritional use only.

Disclaimer: These statements have not been evaluated by the Food and Drug Administration (FDA). These products are not meant to diagnose treat or cure any disease or medical condition. Please consult your doctor before starting any exercise or nutritional supplement program or before using these or any product during pregnancy or if you have a serious medical condition.